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Obeticholic acid
- 英文名称:Obeticholic acid
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10824
- cas:459789-99-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10824 |
用途 | 科研检测 |
英文名称 | Obeticholic acid |
包装规格 | 1MG |
CAS编号 | 459789-99-2 |
别名 | Obeticholic acid |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C26H44O4
分子量:420.63
溶剂:DMSO (35 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):FXR agonist
Function / Pharmacology:A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.
分子式:C26H44O4
分子量:420.63
溶剂:DMSO (35 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):FXR agonist
Function / Pharmacology:A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.