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SB-225002
- 英文名称：SB-225002
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10828
- cas：182498-32-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10828 |
| 用途 | 科研检测 |
| 英文名称 | SB-225002 |
| 包装规格 | 1MG |
| CAS编号 | 182498-32-4 |
| 别名 | SB-225002 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C13H10BrN3O4
分子量:352.14
溶剂:DMSO (35 mg/ml) Ethanol (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):CXCR2 antagonist
Function / Pharmacology:Potent and selective CXCR2 receptor antagonist (IC50 = 22 nM). Displays >150-fold selectivity over CXCR1 receptors.1 Induces apoptosis in both wild-type and p53-deficient ovarian cancer cells (OVCA) via p53 activation and by inducing mitotic catastrophe.2 Blocks IL-8-mediated cellular effects such as oxidative stress-induced cellular senescence3 and neutrophil chemotaxis1. Inhibits HIV replication in lymphocytes and macrophages.4 Inhibits endothelial activation and leukocyte recruitment to cerebral microvessels during neuroinflammation.5
分子式:C13H10BrN3O4
分子量:352.14
溶剂:DMSO (35 mg/ml) Ethanol (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):CXCR2 antagonist
Function / Pharmacology:Potent and selective CXCR2 receptor antagonist (IC50 = 22 nM). Displays >150-fold selectivity over CXCR1 receptors.1 Induces apoptosis in both wild-type and p53-deficient ovarian cancer cells (OVCA) via p53 activation and by inducing mitotic catastrophe.2 Blocks IL-8-mediated cellular effects such as oxidative stress-induced cellular senescence3 and neutrophil chemotaxis1. Inhibits HIV replication in lymphocytes and macrophages.4 Inhibits endothelial activation and leukocyte recruitment to cerebral microvessels during neuroinflammation.5
