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Z-DEVD-FMK
- 英文名称:Z-DEVD-FMK
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10842
- cas:210344-95-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10842 |
用途 | 科研检测 |
英文名称 | Z-DEVD-FMK |
包装规格 | 1MG |
CAS编号 | 210344-95-9 |
别名 | Z-DEVD-FMK |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC,;NMR (Conforms)
分子式:C30H41FN4O12
分子量:668.67
溶剂:DMSO (20 mg/ml)
性状:Lyophilized solid
存储:-20°C
Activity (short version):Caspase3 inhibitor (cell permeable)
Function / Pharmacology:Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5
分子式:C30H41FN4O12
分子量:668.67
溶剂:DMSO (20 mg/ml)
性状:Lyophilized solid
存储:-20°C
Activity (short version):Caspase3 inhibitor (cell permeable)
Function / Pharmacology:Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5