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Leelamine HCl
- 英文名称:Leelamine HCl
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10852
- cas:16496-99-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-07-15
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10852 |
用途 | 科研检测 |
英文名称 | Leelamine HCl |
包装规格 | 1MG |
CAS编号 | 16496-99-4 |
别名 | Leelamine HCl |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C20H31N ? HCl
分子量:321.93
溶剂:DMSO (40 mg/ml) Water (9 mg/ml)
性状:Off-white or beige solid
存储:-20°C
Activity (short version):Intracellular cholesterol inhibitor
Function / Pharmacology:A lysosomotropic, intracellular cholesterol transport inhibitor with potential chemotherapeutic activity. Induces cholesterol accumulation in lysosomal/endosomal cell compartments via inhibition of autophagic flux.1 Induces apoptosis in breast cancer2, melanoma3 and prostate cancer cells4. A selective inducer of cytochrome P450 2B.5 Inhibits pyruvate dehydrogenase kinase (PDK), IC50=9.5 μM.6
分子式:C20H31N ? HCl
分子量:321.93
溶剂:DMSO (40 mg/ml) Water (9 mg/ml)
性状:Off-white or beige solid
存储:-20°C
Activity (short version):Intracellular cholesterol inhibitor
Function / Pharmacology:A lysosomotropic, intracellular cholesterol transport inhibitor with potential chemotherapeutic activity. Induces cholesterol accumulation in lysosomal/endosomal cell compartments via inhibition of autophagic flux.1 Induces apoptosis in breast cancer2, melanoma3 and prostate cancer cells4. A selective inducer of cytochrome P450 2B.5 Inhibits pyruvate dehydrogenase kinase (PDK), IC50=9.5 μM.6