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Embelin
- 英文名称：Embelin
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10855
- cas：550-24-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10855 |
| 用途 | 科研检测 |
| 英文名称 | Embelin |
| 包装规格 | 1MG |
| CAS编号 | 550-24-3 |
| 别名 | Embelin |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C17H26O4
分子量:294.39
溶剂:DMSO (30 mg/ml) Ethanol (3 mg/ml)
性状:Dark orange solid
存储:-20°C
Activity (short version):XIAP inhibitor, Apoptosis inducer
Function / Pharmacology:Inhibits the lysine acetyl transferase PCAF in vitro and in vivo (in vitro IC50=7.2 μM). Inhibits H3K9 acetylation in mouse liver tissue while leaving levels of H3K14, H4K8, H4K12 unchanged1. Also inhibits X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 μM, competing with Smac peptide). Binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Induces apoptosis and alters gene expression profiles in breast cancer cells3. Possesses anti-inflammatory and analgesic activity in vivo4. Cell-permeable.
分子式:C17H26O4
分子量:294.39
溶剂:DMSO (30 mg/ml) Ethanol (3 mg/ml)
性状:Dark orange solid
存储:-20°C
Activity (short version):XIAP inhibitor, Apoptosis inducer
Function / Pharmacology:Inhibits the lysine acetyl transferase PCAF in vitro and in vivo (in vitro IC50=7.2 μM). Inhibits H3K9 acetylation in mouse liver tissue while leaving levels of H3K14, H4K8, H4K12 unchanged1. Also inhibits X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 μM, competing with Smac peptide). Binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Induces apoptosis and alters gene expression profiles in breast cancer cells3. Possesses anti-inflammatory and analgesic activity in vivo4. Cell-permeable.
