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PAC-1
- 英文名称：PAC-1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10859
- cas：315183-21-2
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-12-08
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10859 |
| 用途 | 科研检测 |
| 英文名称 | PAC-1 |
| 包装规格 | 1MG |
| CAS编号 | 315183-21-2 |
| 别名 | PAC-1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C23H28N4O2
分子量:392.49
溶剂:DMSO (35 mg/ml) Ethanol (15 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Procaspase activator
Function / Pharmacology:PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 μM.1 It is less potent at activating procaspase-7, EC50=4.5 μM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3
分子式:C23H28N4O2
分子量:392.49
溶剂:DMSO (35 mg/ml) Ethanol (15 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Procaspase activator
Function / Pharmacology:PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 μM.1 It is less potent at activating procaspase-7, EC50=4.5 μM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3
