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Torin 1
- 英文名称：Torin 1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10868
- cas：1222998-36-8
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10868 |
| 用途 | 科研检测 |
| 英文名称 | Torin 1 |
| 包装规格 | 1MG |
| CAS编号 | 1222998-36-8 |
| 别名 | Torin 1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C35H28F3N5O2
分子量:607.62
溶剂:DMSO (8 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):mTOR inhibitor
Function / Pharmacology:Potent and selective ATP-competitive mTOR inhibitor, IC50=2 and 10 nM for mTORC1 and mTORC2 respectively.1,2 Active in vivo at inhibition of mTOR-mediated effects in mice (20 mg/kg).2 Induces autophagy.3 Torin 1-mediated enhancement of TFEB-mediated autophagy alleviates neuronal death in oxidative stress-induced disease models.4 Downregulates NGF expression in RSC96 cells.5
分子式:C35H28F3N5O2
分子量:607.62
溶剂:DMSO (8 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):mTOR inhibitor
Function / Pharmacology:Potent and selective ATP-competitive mTOR inhibitor, IC50=2 and 10 nM for mTORC1 and mTORC2 respectively.1,2 Active in vivo at inhibition of mTOR-mediated effects in mice (20 mg/kg).2 Induces autophagy.3 Torin 1-mediated enhancement of TFEB-mediated autophagy alleviates neuronal death in oxidative stress-induced disease models.4 Downregulates NGF expression in RSC96 cells.5
