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Homoharringtonine
- 英文名称：Homoharringtonine
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10874
- cas：26833-87-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10874 |
| 用途 | 科研检测 |
| 英文名称 | Homoharringtonine |
| 包装规格 | 1MG |
| CAS编号 | 26833-87-4 |
| 别名 | Homoharringtonine |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:95% by HPLC;NMR (Conforms)
分子式:C29H39NO9
分子量:545.63
溶剂:DMSO (75 mg/ml)
性状:Pale yellow to off-white solid
存储:-20°C
Activity (short version):Protein synthesis inhibitor
Function / Pharmacology:A plant alkaloid, originally isolated from the Hainan plum yew, that binds to the large ribosomal subunit A-site, competing with aminoacyl-tRNA amino acid side chains, thereby inhibiting the initial elongation step of protein synthesis.1 It also binds to transcription factors NKRF (NF-κB repressing factor) and SP1, down-regulating the Myc pathway.2,3 Dramatically decreases global DNA 5-hydroxymethylcytosine levels via the SP1/TET1 axis.3 Induces apoptosis in tyrosine kinase inhibitor-resistant NSCLC cells4, and is a clinically useful agent for CML and AML5.
分子式:C29H39NO9
分子量:545.63
溶剂:DMSO (75 mg/ml)
性状:Pale yellow to off-white solid
存储:-20°C
Activity (short version):Protein synthesis inhibitor
Function / Pharmacology:A plant alkaloid, originally isolated from the Hainan plum yew, that binds to the large ribosomal subunit A-site, competing with aminoacyl-tRNA amino acid side chains, thereby inhibiting the initial elongation step of protein synthesis.1 It also binds to transcription factors NKRF (NF-κB repressing factor) and SP1, down-regulating the Myc pathway.2,3 Dramatically decreases global DNA 5-hydroxymethylcytosine levels via the SP1/TET1 axis.3 Induces apoptosis in tyrosine kinase inhibitor-resistant NSCLC cells4, and is a clinically useful agent for CML and AML5.
