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Nilvadipine
- 英文名称:Nilvadipine
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10875
- cas:75530-68-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10875 |
用途 | 科研检测 |
英文名称 | Nilvadipine |
包装规格 | 1MG |
CAS编号 | 75530-68-6 |
别名 | Nilvadipine |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C19H19N3O6
分子量:385.38
溶剂:DMSO (25 mg/ml) Ethanol (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Syk inhibitor and Ca channel blocker
Function / Pharmacology:A novel DHP L-type Ca2+ channel blocker that also inhibits Syk.1 Blocks Aβ production, APPβ secretion and reduces BACE-1 expression in CHO cells over-expressing Aβ in vitro. Enhances clearance of Aβ across the blood brain barrier in vivo. Reduces brain Aβ levels in a mouse tauopathy model.1 Clinically useful antihypertensive agent.2 Has been shown to prevent cognitive decline in some clinical trials.3 Produces a protective effect on glutamate neurotoxicity in retinal ganglion cells, an effect not shared by other L-type Ca2+ channel blockers such as nifedipine and diltiazem.4
分子式:C19H19N3O6
分子量:385.38
溶剂:DMSO (25 mg/ml) Ethanol (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Syk inhibitor and Ca channel blocker
Function / Pharmacology:A novel DHP L-type Ca2+ channel blocker that also inhibits Syk.1 Blocks Aβ production, APPβ secretion and reduces BACE-1 expression in CHO cells over-expressing Aβ in vitro. Enhances clearance of Aβ across the blood brain barrier in vivo. Reduces brain Aβ levels in a mouse tauopathy model.1 Clinically useful antihypertensive agent.2 Has been shown to prevent cognitive decline in some clinical trials.3 Produces a protective effect on glutamate neurotoxicity in retinal ganglion cells, an effect not shared by other L-type Ca2+ channel blockers such as nifedipine and diltiazem.4