纯度:98% by TLC,;NMR (Conforms)
分子式:C17H38BrN
分子量:336.39
溶剂:DMSO (10 mg/ml) Water (30 mg/ml) Ethanol (60 mg/ml)
性状:White solid
存储:RT
Activity (short version):Dynamin inhibitor
Function / Pharmacology:Dynamin I/II inhibitor targeting the dynamin-phospholipid interaction and inhibiting dynamin GTPase activity with a Ki=940nM.1 Rapidly and reversibly inhibits multiple forms of endocytosis with no acute cellular damage1. A useful pharmacological tool for studying dynamin-mediated trafficking events.2 Induces cytokinesis failure and apoptosis in human cancer cells.3\ Induces cytoprotective autophagy in human Jurkat T cells.4