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Z-Phe-Tyr-CHO
  • 英文名称:Z-Phe-Tyr-CHO
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B10883
  • cas:167498-29-5
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-12
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B10883
用途 科研检测
英文名称 Z-Phe-Tyr-CHO
包装规格 1MG
CAS编号 167498-29-5
别名 Z-Phe-Tyr-CHO
纯度 98+%
分子式
是否进口
纯度:98% by TLC,;NMR (Conforms)
分子式:C26H26N2O5
分子量:446.50
溶剂:DMSO (30 mg/ml) Ethanol (50 mg/ml)
性状:Off-white to pale yellow solid
存储:-20°C
Activity (short version):Cathepsin L inhibitor
Function / Pharmacology:A potent and selective inhibitor of cathepsin L, IC50=0.85 nM 1 selective over cathepsin B and calpain II (IC50s=85.1 and 184 nM respectively). Suppresses osteoclastic pit formation at 1.5 nM and markedly inhibited parathyroid hormone-stimulated osteoclastic bone resorption.2 Also inhibits cathepsin K (Kis=0.052 and 1.57 nM for cat L and cat K respectively) and partially provides the basis for the finding that cathepsin K is the protease responsible for osteoclastic bone resorption.3 Provides partial protection against serum and potassium deprivation-induced neuronal death.4 Active in vivo.2
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