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ABT-263
- 英文名称：ABT-263
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10890
- cas：923564-51-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-11-17
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10890 |
| 用途 | 科研检测 |
| 英文名称 | ABT-263 |
| 包装规格 | 1MG |
| CAS编号 | 923564-51-6 |
| 别名 | ABT-263 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC (NMR Conforms)
分子式:C47H55ClF3N5O6S3
分子量:974.6
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Bcl-2 family inhibitor, Senolytic agent
Function / Pharmacology:Potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A useful tool compound which has shown interesting results in various cancer clinical trials2. Synergizes with deoxyglucose and other agents, inducing apoptosis in cancer cells in a xenograft mouse model3. A novel senolytic agent, inducing apoptosis preferentially in senescent cells in a cell type-restricted manner4.
分子式:C47H55ClF3N5O6S3
分子量:974.6
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Bcl-2 family inhibitor, Senolytic agent
Function / Pharmacology:Potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A useful tool compound which has shown interesting results in various cancer clinical trials2. Synergizes with deoxyglucose and other agents, inducing apoptosis in cancer cells in a xenograft mouse model3. A novel senolytic agent, inducing apoptosis preferentially in senescent cells in a cell type-restricted manner4.
