纯度:98% by TLC;NMR (Conforms)
分子式:C14H21N3O5
分子量:311.33
溶剂:DMSO (30 mg/ml)
性状:white solid
存储:-20°C
Activity (short version):Neuroinflammation inhibitor
Function / Pharmacology:Inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathways.1 Inhibits the formation of advanced glycation end products.2 Ameliorates cognitive dysfunction by antagonizing exocytotoxic glutamate insults and inhibiting autophagy.3 Attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4.4 Attenuates early atherosclerotic lesions in hypercholest-erolemic rabbits via modulation of the inflammatory and oxidative stress pathways.5