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Cabozantinib
- 英文名称：Cabozantinib
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10902
- cas：849217-68-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10902 |
| 用途 | 科研检测 |
| 英文名称 | Cabozantinib |
| 包装规格 | 1MG |
| CAS编号 | 849217-68-1 |
| 别名 | Cabozantinib |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C28H24FN3O5
分子量:501.51
溶剂:DMSO
性状:White solid
存储:-20°C
Activity (short version):Met and VEGFR2 inhibitor
Function / Pharmacology:Novel inhibitor of c-met and VEGFR2 kinase activity, IC50=3.5 nm and 35 pM respectively.1 Inhibits MET-activating kinase domain mutations Y1248H, D1246N or K1262R, IC50=3.8, 11.8 and 14.6 nM respectively. In cellular assays it inhibits the following kinases: MET, VEGF2, KIT, FLT3 and AXL, IC50=7.8, 1.9, 5.0, 7.5 and 42 μM respectively.1 Eliminated approximately 80% of vasculature in spontaneous pancreatic islet tumors over 7 days in a mouse model.2 Clinically useful anticancer agent.3
分子式:C28H24FN3O5
分子量:501.51
溶剂:DMSO
性状:White solid
存储:-20°C
Activity (short version):Met and VEGFR2 inhibitor
Function / Pharmacology:Novel inhibitor of c-met and VEGFR2 kinase activity, IC50=3.5 nm and 35 pM respectively.1 Inhibits MET-activating kinase domain mutations Y1248H, D1246N or K1262R, IC50=3.8, 11.8 and 14.6 nM respectively. In cellular assays it inhibits the following kinases: MET, VEGF2, KIT, FLT3 and AXL, IC50=7.8, 1.9, 5.0, 7.5 and 42 μM respectively.1 Eliminated approximately 80% of vasculature in spontaneous pancreatic islet tumors over 7 days in a mouse model.2 Clinically useful anticancer agent.3
