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2-AAPA
- 英文名称:2-AAPA
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10904
- cas:1133387-90-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10904 |
用途 | 科研检测 |
英文名称 | 2-AAPA |
包装规格 | 1MG |
CAS编号 | 1133387-90-2 |
别名 | 2-AAPA |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC
分子式:C18H22N4O6S4
分子量:518.65
溶剂:DMSO (50 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Glutathione and thioredoxin reductase inhibitor
Function / Pharmacology:Inhibits glutathione reductase and thioredoxin reductase,IC50s=6.7 and 8.7 μM respectively, and impairs mitochondrial function.1 May be used to induce a cellular model of thiol oxidative stress.2 Enhances sensitivity of cancer cell lines to X-ray irradiation.3 Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in α-tubulin S-glutathionylation-mediated microtubule depolymerization.4 Improves limb revascularization by glutathionylation and subsequent stabilization of HIF-1α.5
分子式:C18H22N4O6S4
分子量:518.65
溶剂:DMSO (50 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Glutathione and thioredoxin reductase inhibitor
Function / Pharmacology:Inhibits glutathione reductase and thioredoxin reductase,IC50s=6.7 and 8.7 μM respectively, and impairs mitochondrial function.1 May be used to induce a cellular model of thiol oxidative stress.2 Enhances sensitivity of cancer cell lines to X-ray irradiation.3 Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in α-tubulin S-glutathionylation-mediated microtubule depolymerization.4 Improves limb revascularization by glutathionylation and subsequent stabilization of HIF-1α.5