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Rucaparib phosphate
- 英文名称：Rucaparib phosphate
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10915
- cas：459868-92-9
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10915 |
| 用途 | 科研检测 |
| 英文名称 | Rucaparib phosphate |
| 包装规格 | 1MG |
| CAS编号 | 459868-92-9 |
| 别名 | Rucaparib phosphate |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C19H18FN3O ? H3PO4
分子量:421.36
溶剂:DMSO (25 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):PARP1 inhibitor
Function / Pharmacology:Rucaparib is a potent (Ki<5 nM) PARP1 inhibitor.1 Cytotoxic to human cancer cells or xenograft tumors with mutated or epigenetically silenced BRCA1/2.2 Demonstrates antiproliferative effects in 26 out of 39 ovarian cancer cell lines.3 Synergizes with other anticancer agents such as topotecan, carboplatin, doxorubicin, paclitaxel3 and temozolamide.4 Ameliorates the cardiotoxicity of doxorubicin.5 Recently approved for human use by the FDA.
分子式:C19H18FN3O ? H3PO4
分子量:421.36
溶剂:DMSO (25 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):PARP1 inhibitor
Function / Pharmacology:Rucaparib is a potent (Ki<5 nM) PARP1 inhibitor.1 Cytotoxic to human cancer cells or xenograft tumors with mutated or epigenetically silenced BRCA1/2.2 Demonstrates antiproliferative effects in 26 out of 39 ovarian cancer cell lines.3 Synergizes with other anticancer agents such as topotecan, carboplatin, doxorubicin, paclitaxel3 and temozolamide.4 Ameliorates the cardiotoxicity of doxorubicin.5 Recently approved for human use by the FDA.
