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CK-666
- 英文名称:CK-666
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10918
- cas:442633-00-3
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10918 |
用途 | 科研检测 |
英文名称 | CK-666 |
包装规格 | 1MG |
CAS编号 | 442633-00-3 |
别名 | CK-666 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C18H17FN2O
分子量:296.34
溶剂:DMSO (45 mg/ml) Ethanol (30 mg/ml)
性状:Cream-colored solid
存储:-20°C
Activity (short version):ARP2/3 inhibitor
Function / Pharmacology:A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 μM for human ARP2/3.1 Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine3. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.
分子式:C18H17FN2O
分子量:296.34
溶剂:DMSO (45 mg/ml) Ethanol (30 mg/ml)
性状:Cream-colored solid
存储:-20°C
Activity (short version):ARP2/3 inhibitor
Function / Pharmacology:A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 μM for human ARP2/3.1 Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine3. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.