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T0901317
- 英文名称:T0901317
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10919
- cas:293754-55-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10919 |
用途 | 科研检测 |
英文名称 | T0901317 |
包装规格 | 1MG |
CAS编号 | 293754-55-9 |
别名 | T0901317 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C17H12F9NO3S
分子量:481.33
溶剂:DMSO (50 mg/ml) Ethanol (50 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):LXR agonist
Function / Pharmacology:Potent high affinity liver X receptor (LXRα and β) agonist, EC50~50 nM.1 Upregulates expression of ABCA1, a reverse cholesterol transporter, resulting in inhibition of cholesterol absorption. Inverse agonist at CAR.2 T0901317 was also shown to be an FXR agonist at lower potency than LXR thus appropriate controls must be employed when using this compound as a pharmacological tool.3 Decreases amyloid beta production in a mouse model of Alzheimer’s disease.4 Inhibits cellular senescence in endothelial cells.5
分子式:C17H12F9NO3S
分子量:481.33
溶剂:DMSO (50 mg/ml) Ethanol (50 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):LXR agonist
Function / Pharmacology:Potent high affinity liver X receptor (LXRα and β) agonist, EC50~50 nM.1 Upregulates expression of ABCA1, a reverse cholesterol transporter, resulting in inhibition of cholesterol absorption. Inverse agonist at CAR.2 T0901317 was also shown to be an FXR agonist at lower potency than LXR thus appropriate controls must be employed when using this compound as a pharmacological tool.3 Decreases amyloid beta production in a mouse model of Alzheimer’s disease.4 Inhibits cellular senescence in endothelial cells.5