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CU-CPT8m
- 英文名称:CU-CPT8m
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10922
- cas:125079-83-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10922 |
用途 | 科研检测 |
英文名称 | CU-CPT8m |
包装规格 | 1MG |
CAS编号 | 125079-83-6 |
别名 | CU-CPT8m |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC,;NMR (Conforms)
分子式:C14H12N4O
分子量:
溶剂:DMSO (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):TLR8 antagonist
Function / Pharmacology:CU-CPT8m is a potent and selective antagonist of toll-like receptor 8 (TLR8) acting via stabilization of the TLR8 homodimer.1 It inhibits TNFα and IL-8 expression induced by the TLR8 agonist resiquimod at 1 mM and suppresses TLR8-mediated proinflammatory signaling in various cell lines, human primary cells and patient specimens. It reverses phenotypes involved in TLR8-activating fibroblasts.2 CU-CPT8m promotes erythroid cell proliferation and differentiation.3
分子式:C14H12N4O
分子量:
溶剂:DMSO (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):TLR8 antagonist
Function / Pharmacology:CU-CPT8m is a potent and selective antagonist of toll-like receptor 8 (TLR8) acting via stabilization of the TLR8 homodimer.1 It inhibits TNFα and IL-8 expression induced by the TLR8 agonist resiquimod at 1 mM and suppresses TLR8-mediated proinflammatory signaling in various cell lines, human primary cells and patient specimens. It reverses phenotypes involved in TLR8-activating fibroblasts.2 CU-CPT8m promotes erythroid cell proliferation and differentiation.3