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AC1903
- 英文名称:AC1903
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10923
- cas:831234-13-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10923 |
用途 | 科研检测 |
英文名称 | AC1903 |
包装规格 | 1MG |
CAS编号 | 831234-13-0 |
别名 | AC1903 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C19H17N3O
分子量:303.36
溶剂:DMSO (30 mg/ml) Ethanol (25 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):TRPC5 blocker
Function / Pharmacology:A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
分子式:C19H17N3O
分子量:303.36
溶剂:DMSO (30 mg/ml) Ethanol (25 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):TRPC5 blocker
Function / Pharmacology:A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.