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AC1903
- 英文名称：AC1903
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10923
- cas：831234-13-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10923 |
| 用途 | 科研检测 |
| 英文名称 | AC1903 |
| 包装规格 | 1MG |
| CAS编号 | 831234-13-0 |
| 别名 | AC1903 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C19H17N3O
分子量:303.36
溶剂:DMSO (30 mg/ml) Ethanol (25 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):TRPC5 blocker
Function / Pharmacology:A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
分子式:C19H17N3O
分子量:303.36
溶剂:DMSO (30 mg/ml) Ethanol (25 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):TRPC5 blocker
Function / Pharmacology:A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
