纯度:>98% by HPLC,;NMR (Conforms)
分子式:C33H37N5O5 ? CH3SO3H
分子量:679.79
溶剂:DMSO (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Vascular serotonin receptor agonist
Function / Pharmacology:Dihydroergotamine mesylate (6190-39-2) is a full agonist at serotonin 5HT1B and 5HT1D receptors, IC50= 2 and 2.2 nM respectively1 and also at 5HT1A and 5HT1F receptors2. One of the oldest agents for treatment of migraine.3 Also acts as a potent vasoconstrictor and alpha-adrenergic antagonist.4