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VGX1027
  • 英文名称:VGX1027
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B10930
  • cas:6501-72-0
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-23
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B10930
用途 科研检测
英文名称 VGX1027
包装规格 1MG
CAS编号 6501-72-0
别名 VGX1027
纯度 98+%
分子式
是否进口
纯度:98% by HPLC
分子式:C11H11NO3
分子量:205.2
溶剂:DMSO (30 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Immunomodulator cytokine release inhibitor
Function / Pharmacology:Immunomodulator. Inhibits secretion of IL-1β, TNF-α, and IL-10 from murine macrophages stimulated with LPS and spares T cell function.1 Ameliorates the course of acute and chronic immunoinflammatory conditions such as carrageenan-induced pleurisy, LPS-induced lethality and type II collagen-induced arthritis in mouse models.1 Prevents spontaneous and accelerated forms of autoimmune diabetes in a NOD mouse model.2 Moldulates genes involved in LPS-induced Toll-like receptor 4 activation in a mouse Lupus model.3 Displays protective effects in particulate matter-induced acute lung injury by blocking TLR4 signaling.4
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