纯度:>98% by HPLC,;NMR (Conforms)
分子式:C23H21ClN2O5
分子量:440.88
溶剂:DMSO (45 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):GPX4 inhibitor / Ferroptosis inducer
Function / Pharmacology:RSL3 inhibits glutathione peroxidase (GPX4) inducing ferroptosis.1,2 Effectively induces ferroptosis in glioblastoma cells.3 Everolimus in combination with RSL3 synergistically inhibits the viability of renal cell carcinoma (RCC) cells suggesting a mechanism by which RCC drug resistance may be overcome.4