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TPPU
- 英文名称：TPPU
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10937
- cas：1222780-33-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-16
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10937 |
| 用途 | 科研检测 |
| 英文名称 | TPPU |
| 包装规格 | 1MG |
| CAS编号 | 1222780-33-7 |
| 别名 | TPPU |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C16H20F3N3O3
分子量:359.35
溶剂:DMSO (40 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Soluble epoxide hydrolase inhibitor
Function / Pharmacology:TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.
分子式:C16H20F3N3O3
分子量:359.35
溶剂:DMSO (40 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Soluble epoxide hydrolase inhibitor
Function / Pharmacology:TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.
