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TPPU
- 英文名称:TPPU
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10937
- cas:1222780-33-7
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10937 |
用途 | 科研检测 |
英文名称 | TPPU |
包装规格 | 1MG |
CAS编号 | 1222780-33-7 |
别名 | TPPU |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C16H20F3N3O3
分子量:359.35
溶剂:DMSO (40 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Soluble epoxide hydrolase inhibitor
Function / Pharmacology:TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.
分子式:C16H20F3N3O3
分子量:359.35
溶剂:DMSO (40 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Soluble epoxide hydrolase inhibitor
Function / Pharmacology:TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.