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Autophinib
- 英文名称:Autophinib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10940
- cas:1644443-47-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10940 |
用途 | 科研检测 |
英文名称 | Autophinib |
包装规格 | 1MG |
CAS编号 | 1644443-47-9 |
别名 | Autophinib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C14H11ClN6O3
分子量:346.73
溶剂:DMSO (30 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Autophagy inhibitor
Function / Pharmacology:Inhibits autophagy induced by starvation or rapamycin by inhibiting the lipid kinase VPS34 (IC50=19 nM).1 Increased autophagy and apoptosis were rescued by autophinib in Per1-overexpressing oral squamous cell carcinoma cells.2 Autophinib has quickly become an important biochemical tool for inhibition of autophagy in a variety of cellular contexts.3-5
分子式:C14H11ClN6O3
分子量:346.73
溶剂:DMSO (30 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Autophagy inhibitor
Function / Pharmacology:Inhibits autophagy induced by starvation or rapamycin by inhibiting the lipid kinase VPS34 (IC50=19 nM).1 Increased autophagy and apoptosis were rescued by autophinib in Per1-overexpressing oral squamous cell carcinoma cells.2 Autophinib has quickly become an important biochemical tool for inhibition of autophagy in a variety of cellular contexts.3-5