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Verteporfin
- 英文名称:Verteporfin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10942
- cas:129497-78-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10942 |
用途 | 科研检测 |
英文名称 | Verteporfin |
包装规格 | 1MG |
CAS编号 | 129497-78-5 |
别名 | Verteporfin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C41H42N4O8
分子量:718.79
溶剂:DMSO (14 mg/ml)
性状:Black solid
存储:-20°C
Activity (short version):YAP inhibitor
Function / Pharmacology:Verteporfin inhibits transcription by YAP/TAZ, IC50 = 2.5 μM, (via disruption of YAP-TEAD interaction) inhibiting autophagy and halting proliferation of cancer and cancer stem cell lines.1,2 Inhibits autophagosome formation.3 Reverses differentiation of Src-overexpressing embryonic stem cells.4 May be used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals.5
分子式:C41H42N4O8
分子量:718.79
溶剂:DMSO (14 mg/ml)
性状:Black solid
存储:-20°C
Activity (short version):YAP inhibitor
Function / Pharmacology:Verteporfin inhibits transcription by YAP/TAZ, IC50 = 2.5 μM, (via disruption of YAP-TEAD interaction) inhibiting autophagy and halting proliferation of cancer and cancer stem cell lines.1,2 Inhibits autophagosome formation.3 Reverses differentiation of Src-overexpressing embryonic stem cells.4 May be used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals.5