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AA43279
- 英文名称：AA43279
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10946
- cas：354812-16-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10946 |
| 用途 | 科研检测 |
| 英文名称 | AA43279 |
| 包装规格 | 1MG |
| CAS编号 | 354812-16-1 |
| 别名 | AA43279 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:97% by TLC;NMR (Conforms)
分子式:C12H12N2O2S
分子量:248.30
溶剂:DMSO (35 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):Nav 1.1 activator
Function / Pharmacology:Selective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 μM). In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1
分子式:C12H12N2O2S
分子量:248.30
溶剂:DMSO (35 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):Nav 1.1 activator
Function / Pharmacology:Selective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 μM). In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1
