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4-Octyl itaconate
- 英文名称:4-Octyl itaconate
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10952
- cas:3133-16-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10952 |
用途 | 科研检测 |
英文名称 | 4-Octyl itaconate |
包装规格 | 1MG |
CAS编号 | 3133-16-2 |
别名 | 4-Octyl itaconate |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C13H22O4
分子量:242.32
溶剂:DMSO (25 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):Nrf2 activator
Function / Pharmacology:4-Octyl itaconate is a cell-permeable analog of itaconic acid which activates the anti-inflammatory transcription factor Nrf2 via alkylation of KEAP1.1 It inhibits various forms of cell death including ferroptosis2 and gasdermin B-mediated pyroptosis3 while inducing secretion of anti-inflammatory proteins4 and promoting a wound-resolving phenotype in pro-inflammatory macrophages5.
分子式:C13H22O4
分子量:242.32
溶剂:DMSO (25 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):Nrf2 activator
Function / Pharmacology:4-Octyl itaconate is a cell-permeable analog of itaconic acid which activates the anti-inflammatory transcription factor Nrf2 via alkylation of KEAP1.1 It inhibits various forms of cell death including ferroptosis2 and gasdermin B-mediated pyroptosis3 while inducing secretion of anti-inflammatory proteins4 and promoting a wound-resolving phenotype in pro-inflammatory macrophages5.