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SCR7 pyrazine
- 英文名称:SCR7 pyrazine
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10962
- cas:14892-97-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10962 |
用途 | 科研检测 |
英文名称 | SCR7 pyrazine |
包装规格 | 1MG |
CAS编号 | 14892-97-8 |
别名 | SCR7 pyrazine |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C18H12N4OS
分子量:332.38
溶剂:DMSO (35 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):CRISPR enhancer
Function / Pharmacology:SCR7 pyrazine enhances the efficiency of precise genome editing with CRISPR/Cas9 up to 19-fold via inhibition of nonhomologous end joining (NHEJ).1,2 May be employed in an optimized CRISPR/Cas9 method to target methylation in a site-specific manner enabling maintenance of gene silencing in vitro and in vivo.3 SCR7 pyrazine exhibits greater activity against DNA ligases I and III than DNA ligase IV.4 Induces cancer cell death via inhibition of NHEJ and potentiates the effect of double strand break-inducing therapeutic modalities.4,5
分子式:C18H12N4OS
分子量:332.38
溶剂:DMSO (35 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):CRISPR enhancer
Function / Pharmacology:SCR7 pyrazine enhances the efficiency of precise genome editing with CRISPR/Cas9 up to 19-fold via inhibition of nonhomologous end joining (NHEJ).1,2 May be employed in an optimized CRISPR/Cas9 method to target methylation in a site-specific manner enabling maintenance of gene silencing in vitro and in vivo.3 SCR7 pyrazine exhibits greater activity against DNA ligases I and III than DNA ligase IV.4 Induces cancer cell death via inhibition of NHEJ and potentiates the effect of double strand break-inducing therapeutic modalities.4,5