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NLRP3i
- 英文名称:NLRP3i
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10965
- cas:16673-34-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10965 |
用途 | 科研检测 |
英文名称 | NLRP3i |
包装规格 | 1MG |
CAS编号 | 16673-34-0 |
别名 | NLRP3i |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C16H17ClN2O4S
分子量:368.84
溶剂:DMSO (45 mg/ml)
性状:White solid
存储:RT
Activity (short version):NLRP3 inflammasome inhibitor
Function / Pharmacology:NLRP3 inflammasome inhibitor which likely acts via interfering with the formation of the NLRP3 inflammasome complex and which exhibits promising in vivo protective activities in mouse acute myocardial infarction models. It blocks ASC aggregation, blocks the release of IL-1? and the activation of caspase-1 in macrophages expressing constitutively active NLRP3 but does not directly inhibit caspase-1.1,2 Limits infarct size after myocardial ischemia-reperfusion as well as leukocyte infiltration in a peritonitis model in mice.2
分子式:C16H17ClN2O4S
分子量:368.84
溶剂:DMSO (45 mg/ml)
性状:White solid
存储:RT
Activity (short version):NLRP3 inflammasome inhibitor
Function / Pharmacology:NLRP3 inflammasome inhibitor which likely acts via interfering with the formation of the NLRP3 inflammasome complex and which exhibits promising in vivo protective activities in mouse acute myocardial infarction models. It blocks ASC aggregation, blocks the release of IL-1? and the activation of caspase-1 in macrophages expressing constitutively active NLRP3 but does not directly inhibit caspase-1.1,2 Limits infarct size after myocardial ischemia-reperfusion as well as leukocyte infiltration in a peritonitis model in mice.2