纯度:98% by TLC,;NMR (Conforms)
分子式:C11H9ClF3NO2
分子量:279.64
溶剂:DMSO (28 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Glucose uptake inhibitor
Function / Pharmacology:A novel inhibitor of glucose uptake which acts via inhibition of the glucose transporter GluT1 and GluT4 (IC50=68 ?M).1 Inhibition of glucose uptake is cell type specific2 and is a promising approach to new cancer therapeutics3. Rescues cardiac progenitor cell dysfunction and mitochondrial fission induced by high glucose4. Sensitizes cells to FAS-induced cell death.5,6