纯度:98% by TLC;NMR (Conforms)
分子式:C30H40BrP
分子量:511.52
溶剂:DMSO (50 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):Mitochondria-targeted cancer stem cell inhibitor
Function / Pharmacology:A mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 ?M) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and nicolsamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2