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Dyclonine HCl
- 英文名称：Dyclonine HCl
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10986
- cas：536-43-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-16
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10986 |
| 用途 | 科研检测 |
| 英文名称 | Dyclonine HCl |
| 包装规格 | 1MG |
| CAS编号 | 536-43-6 |
| 别名 | Dyclonine HCl |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C18H27NO2 ? HCl
分子量:325.87
溶剂:DMSO (20 mg/ml) Water (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):Mitochondrial function enhancer
Function / Pharmacology:Dyclonine is a topical anesthetic which has been used for oral and throat analgesia.1 Enhances neuronal mitochondrial function, potentiating respiration and providing protection against insults associated with neurodegenerative disorders.2 Inhibits aldehyde dehydrogenase ALDH3A1 resulting in accumulation of 4-hydroxynonenal, which renders head and neck squamous cell carcinoma cells sensitive to the cystine-glutamate antiporter inhibitor, sulfasalazine.3 Rescues frataxin deficiency in animal models as well as in buccal cells of patients with Friedreich’s Ataxia.4 Enhances the cytotoxic effect of proteasome inhibitors MG-1325 and bortezomib6 in cancer cells.
分子式:C18H27NO2 ? HCl
分子量:325.87
溶剂:DMSO (20 mg/ml) Water (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):Mitochondrial function enhancer
Function / Pharmacology:Dyclonine is a topical anesthetic which has been used for oral and throat analgesia.1 Enhances neuronal mitochondrial function, potentiating respiration and providing protection against insults associated with neurodegenerative disorders.2 Inhibits aldehyde dehydrogenase ALDH3A1 resulting in accumulation of 4-hydroxynonenal, which renders head and neck squamous cell carcinoma cells sensitive to the cystine-glutamate antiporter inhibitor, sulfasalazine.3 Rescues frataxin deficiency in animal models as well as in buccal cells of patients with Friedreich’s Ataxia.4 Enhances the cytotoxic effect of proteasome inhibitors MG-1325 and bortezomib6 in cancer cells.
