纯度:>98% by HPLC;NMR (Conforms)
分子式:C21H14ClN3O
分子量:359.81
溶剂:DMSO (up to 25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Cryptochrome stabilizer
Function / Pharmacology:Potent stabilizer of the circadian clock protein cryptochrome (CRY).1 It lengthened the circadian period and repressed Per2 activity in reporter assays with 10-fold more potency than KL001 (Cat# 10-1411). KL044 inhibited melanogenesis and melanosome transport via suppression of the cAMP/PKA/CREB pathway.2