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IMT1
- 英文名称：IMT1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11001
- cas：2304621-31-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11001 |
| 用途 | 科研检测 |
| 英文名称 | IMT1 |
| 包装规格 | 1MG |
| CAS编号 | 2304621-31-4 |
| 别名 | IMT1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C21H21NO4
分子量:351.4
溶剂:DMSO (at least 50 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Mitochondrial DNA transcription inhibitor/RNA Polymerase inhibitor
Function / Pharmacology:IMT1 (2304621-31-4) is a specific inhibitor of mitochondrial DNA (mtDNA) transcription. It targets an allosteric binding site on human mitochondrial RNA polymerase leading to impairment of biogenesis of the oxidative phosphorylation (OXPHOS) system.1 IMT1 treatment of 89 cancer cell lines lead to a strong decrease in cell viability in one third of them without affecting normal cells. It inhibited proliferation and migration in squamous cell2 and endometrial carcinoma cells3.
分子式:C21H21NO4
分子量:351.4
溶剂:DMSO (at least 50 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Mitochondrial DNA transcription inhibitor/RNA Polymerase inhibitor
Function / Pharmacology:IMT1 (2304621-31-4) is a specific inhibitor of mitochondrial DNA (mtDNA) transcription. It targets an allosteric binding site on human mitochondrial RNA polymerase leading to impairment of biogenesis of the oxidative phosphorylation (OXPHOS) system.1 IMT1 treatment of 89 cancer cell lines lead to a strong decrease in cell viability in one third of them without affecting normal cells. It inhibited proliferation and migration in squamous cell2 and endometrial carcinoma cells3.
