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PY-60
- 英文名称：PY-60
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11007
- cas：2765218-56-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11007 |
| 用途 | 科研检测 |
| 英文名称 | PY-60 |
| 包装规格 | 1MG |
| CAS编号 | 2765218-56-0 |
| 别名 | PY-60 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by HPLC ,;NMR (Conforms)
分子式:C16H15N3O2S
分子量:313.38
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):YAP Activator
Function / Pharmacology:PY-60 (2765218-56-0) activates YAP transcriptional activity (EC50 = 1.6 μM) via delocalization of annexin A2 (ANXA2) from cell membranes leading to Hippo inactivation, a key controller of YAP.1 It was able to induce serum-free expansion of MCF10A cells and epidermal keratinocytes and their precursors ex vivo and in adult mice. PY-60 promoted regenerative repair of cutaneous wounds in pig and human models by enabling a pro-proliferative transcriptional program in keratinocytes and dermal cells that accelerated re-epithelization and regranulation of the wound bed.2
分子式:C16H15N3O2S
分子量:313.38
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):YAP Activator
Function / Pharmacology:PY-60 (2765218-56-0) activates YAP transcriptional activity (EC50 = 1.6 μM) via delocalization of annexin A2 (ANXA2) from cell membranes leading to Hippo inactivation, a key controller of YAP.1 It was able to induce serum-free expansion of MCF10A cells and epidermal keratinocytes and their precursors ex vivo and in adult mice. PY-60 promoted regenerative repair of cutaneous wounds in pig and human models by enabling a pro-proliferative transcriptional program in keratinocytes and dermal cells that accelerated re-epithelization and regranulation of the wound bed.2
