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MAC-545496
- 英文名称：MAC-545496
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11024
- cas：838810-96-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11024 |
| 用途 | 科研检测 |
| 英文名称 | MAC-545496 |
| 包装规格 | 1MG |
| CAS编号 | 838810-96-1 |
| 别名 | MAC-545496 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C18H18ClN5O3S
分子量:419.88
溶剂:DMSO (25 mg/ml)
性状:Yellow/orange solid
存储:-20°C
Activity (short version):GraR inhibitor
Function / Pharmacology:Inhibitor of glycopeptide-resistance-associated protein R (GraR, also known as ApsR). GraR and its regulatory system are important for virulence of S. aureus. MAC-545496 is able to reverse ?-lactam resistance in S. aureus in a G. Mellonella larvae model. 0.06 μg/mL MAC-545496 lowered the minimum inhibitory concentration (MIC) for oxacillin against S. aureus below the CLSI clinical breakpoint. It lowered the ?-lactam MIC from 512 to 8 μg/mL against S. aureus USA300.
分子式:C18H18ClN5O3S
分子量:419.88
溶剂:DMSO (25 mg/ml)
性状:Yellow/orange solid
存储:-20°C
Activity (short version):GraR inhibitor
Function / Pharmacology:Inhibitor of glycopeptide-resistance-associated protein R (GraR, also known as ApsR). GraR and its regulatory system are important for virulence of S. aureus. MAC-545496 is able to reverse ?-lactam resistance in S. aureus in a G. Mellonella larvae model. 0.06 μg/mL MAC-545496 lowered the minimum inhibitory concentration (MIC) for oxacillin against S. aureus below the CLSI clinical breakpoint. It lowered the ?-lactam MIC from 512 to 8 μg/mL against S. aureus USA300.
