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SCR-1481B1
- 英文名称:SCR-1481B1
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11037
- cas:1174161-86-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11037 |
用途 | 科研检测 |
英文名称 | SCR-1481B1 |
包装规格 | 1MG |
CAS编号 | 1174161-86-4 |
别名 | SCR-1481B1 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC ,;NMR (Conforms)
分子式:C24H18ClF2N4O7P·2C4H11NO3
分子量:821.12
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Gasdermin D inhibitor
Function / Pharmacology:SCR-1481B1 is an inhibitor of HGFR (Met) and VEGFR kinases.1 SCR-1481B1 potently suppresses gasdermin D-mediated pyroptosis via targeting of the oligomerization interface I.2 Active in vivo in a mouse model of sepsis. SCR-1481B1 acts synergistically with another gasdermin D inhibitor, Cefcapene pivoxil (Cat #10-3972), and a PD-L1 antibody to significantly enhance the antitumor activity of anti-PD-L1 therapy.
分子式:C24H18ClF2N4O7P·2C4H11NO3
分子量:821.12
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Gasdermin D inhibitor
Function / Pharmacology:SCR-1481B1 is an inhibitor of HGFR (Met) and VEGFR kinases.1 SCR-1481B1 potently suppresses gasdermin D-mediated pyroptosis via targeting of the oligomerization interface I.2 Active in vivo in a mouse model of sepsis. SCR-1481B1 acts synergistically with another gasdermin D inhibitor, Cefcapene pivoxil (Cat #10-3972), and a PD-L1 antibody to significantly enhance the antitumor activity of anti-PD-L1 therapy.