|
Ceapin-A7
- 英文名称：Ceapin-A7
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11040
- cas：2323027-38-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-16
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11040 |
| 用途 | 科研检测 |
| 英文名称 | Ceapin-A7 |
| 包装规格 | 1MG |
| CAS编号 | 2323027-38-7 |
| 别名 | Ceapin-A7 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC ,;NMR (Conforms)
分子式:C20H12F6N4O3
分子量:470.33
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):ATF6a/UPR inhibitor
Function / Pharmacology:Selective inhibitor (IC50 = 590 nM) of transcription factor ATF6α, one of the three branches of the unfolded protein response.1 It inhibits activation of ATF6α in response to ER stress without inhibiting ER-bound transcription factors ATF6? or SREBP or the IRE1 or PERK branches of the UPR. Ceapin-A7 also show no toxicity to unstressed cells. It induces neomorphic association of the ER and peroxisomes by directly tethering the cytosolic domain of ATF6a to the peroxisomal transporter ABCD3 without inhibiting its transporter activity.2 See companion activator 10-3973.
分子式:C20H12F6N4O3
分子量:470.33
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):ATF6a/UPR inhibitor
Function / Pharmacology:Selective inhibitor (IC50 = 590 nM) of transcription factor ATF6α, one of the three branches of the unfolded protein response.1 It inhibits activation of ATF6α in response to ER stress without inhibiting ER-bound transcription factors ATF6? or SREBP or the IRE1 or PERK branches of the UPR. Ceapin-A7 also show no toxicity to unstressed cells. It induces neomorphic association of the ER and peroxisomes by directly tethering the cytosolic domain of ATF6a to the peroxisomal transporter ABCD3 without inhibiting its transporter activity.2 See companion activator 10-3973.
