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C19-9
- 英文名称:C19-9
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11041
- cas:1477482-47-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11041 |
用途 | 科研检测 |
英文名称 | C19-9 |
包装规格 | 1MG |
CAS编号 | 1477482-47-5 |
别名 | C19-9 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C16H18N4O3
分子量:314.35
溶剂:DMSO (>50 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):non-RGD integrin αv?3 receptor inhibitor
Function / Pharmacology:C19-9 (1477482-47-5) is a novel non-RGD inhibitor of the integrin αv?3 receptor (KD = 102 nM). It was active against the human prostate carcinoma epithelial cell line 22RV1 (IC50 = 467 nM) and human prostate cancer organoids (IC50 = 652 nM). C19-9 was active in vivo in 22RV1 mouse xenografts and blocked growth in enzalutamide-resistant mouse CRPC xenografts.
分子式:C16H18N4O3
分子量:314.35
溶剂:DMSO (>50 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):non-RGD integrin αv?3 receptor inhibitor
Function / Pharmacology:C19-9 (1477482-47-5) is a novel non-RGD inhibitor of the integrin αv?3 receptor (KD = 102 nM). It was active against the human prostate carcinoma epithelial cell line 22RV1 (IC50 = 467 nM) and human prostate cancer organoids (IC50 = 652 nM). C19-9 was active in vivo in 22RV1 mouse xenografts and blocked growth in enzalutamide-resistant mouse CRPC xenografts.