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PF-05089771
- 英文名称:PF-05089771
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11045
- cas:1235403-62-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11045 |
用途 | 科研检测 |
英文名称 | PF-05089771 |
包装规格 | 1MG |
CAS编号 | 1235403-62-9 |
别名 | PF-05089771 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C18H12Cl2FN5O3S2
分子量:500.34
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Selective Nav1.7 channel blocker
Function / Pharmacology:Potent and selective inhibitor of the voltage gated sodium channel 1.7 (Nav1.7).1,3 It is a state-dependent inhibitor with IC50 = 11 nM for the half-inactivated channels and IC50 ~ 10 μM for resting channels.1 Equipotent for human, monkey, dog, and mouse channels but 15x less potent for rat channels. Interacts equally with fast and slow inactivated Nav1.7 channels.2
分子式:C18H12Cl2FN5O3S2
分子量:500.34
溶剂:DMSO (>25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Selective Nav1.7 channel blocker
Function / Pharmacology:Potent and selective inhibitor of the voltage gated sodium channel 1.7 (Nav1.7).1,3 It is a state-dependent inhibitor with IC50 = 11 nM for the half-inactivated channels and IC50 ~ 10 μM for resting channels.1 Equipotent for human, monkey, dog, and mouse channels but 15x less potent for rat channels. Interacts equally with fast and slow inactivated Nav1.7 channels.2