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Pridopidine
- 英文名称:Pridopidine
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11051
- cas:346688-38-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11051 |
用途 | 科研检测 |
英文名称 | Pridopidine |
包装规格 | 1MG |
CAS编号 | 346688-38-8 |
别名 | Pridopidine |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C15H23NO2S
分子量:281.41
溶剂:DMSO (>25 mg/mL)
性状:Off-white solid
存储:RT
Activity (short version):Sigma-1 ligand/neuroprotective/restorative
Function / Pharmacology:Pridopidine is being studied as a potential treatment for Huntington’s disease, Parkinson’s disease, and schizophrenia based on its locomotor stabilizing and antipsychotic-like effects.1,2 It was, unusually, able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics (“dopamine stabilizer”).3 More recent studies have attributed pridopidine's effects to its being a more potent sigma-1 ligand than a D2 ligand.4,5 Displays neuroprotective/restorative effects6,7 and ameliorates central features of amyotrophic lateral sclerosis pathology8 in a sigma-1-mediated manner
分子式:C15H23NO2S
分子量:281.41
溶剂:DMSO (>25 mg/mL)
性状:Off-white solid
存储:RT
Activity (short version):Sigma-1 ligand/neuroprotective/restorative
Function / Pharmacology:Pridopidine is being studied as a potential treatment for Huntington’s disease, Parkinson’s disease, and schizophrenia based on its locomotor stabilizing and antipsychotic-like effects.1,2 It was, unusually, able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics (“dopamine stabilizer”).3 More recent studies have attributed pridopidine's effects to its being a more potent sigma-1 ligand than a D2 ligand.4,5 Displays neuroprotective/restorative effects6,7 and ameliorates central features of amyotrophic lateral sclerosis pathology8 in a sigma-1-mediated manner