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Pridopidine
  • 英文名称:Pridopidine
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B11051
  • cas:346688-38-8
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-23
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B11051
用途 科研检测
英文名称 Pridopidine
包装规格 1MG
CAS编号 346688-38-8
别名 Pridopidine
纯度 98+%
分子式
是否进口
纯度:98% by TLC;NMR (Conforms)
分子式:C15H23NO2S
分子量:281.41
溶剂:DMSO (>25 mg/mL)
性状:Off-white solid
存储:RT
Activity (short version):Sigma-1 ligand/neuroprotective/restorative
Function / Pharmacology:Pridopidine is being studied as a potential treatment for Huntington’s disease, Parkinson’s disease, and schizophrenia based on its locomotor stabilizing and antipsychotic-like effects.1,2 It was, unusually, able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics (“dopamine stabilizer”).3 More recent studies have attributed pridopidine's effects to its being a more potent sigma-1 ligand than a D2 ligand.4,5 Displays neuroprotective/restorative effects6,7 and ameliorates central features of amyotrophic lateral sclerosis pathology8 in a sigma-1-mediated manner
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