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MPEP HCl
- 英文名称：MPEP HCl
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11055
- cas：219911-35-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11055 |
| 用途 | 科研检测 |
| 英文名称 | MPEP HCl |
| 包装规格 | 1MG |
| CAS编号 | 219911-35-0 |
| 别名 | MPEP HCl |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C14H11N·HCl
分子量:229.71
溶剂:DMSO (20 mg/ml) Ethanol (20 mg/ml)
性状:White or pale yellow solid
存储:-20°C
Activity (short version):mGlu5 receptor antagonist
Function / Pharmacology:MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5).1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinson’s3,4, Fragile X syndrome5, and addiction6.
分子式:C14H11N·HCl
分子量:229.71
溶剂:DMSO (20 mg/ml) Ethanol (20 mg/ml)
性状:White or pale yellow solid
存储:-20°C
Activity (short version):mGlu5 receptor antagonist
Function / Pharmacology:MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5).1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinson’s3,4, Fragile X syndrome5, and addiction6.
