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Selinexor
- 英文名称：Selinexor
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11059
- cas：1393477-72-9
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11059 |
| 用途 | 科研检测 |
| 英文名称 | Selinexor |
| 包装规格 | 1MG |
| CAS编号 | 1393477-72-9 |
| 别名 | Selinexor |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C17H11F6N7O
分子量:443.31
溶剂:DMSO (>25 mg/ml) Ethanol (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):CRM1/XPO1 nuclear export receptor inhibitor
Function / Pharmacology:Selinexor is a potent inhibitor of the nuclear export receptor, chromosome region maintenance 1 (CRM1; Exportin-1 (XPO1)). It exhibited potent growth suppression in various T-cell acute lymphoblastic leukemia (T-ALL) cells (IC50’s = 34-203 nM)1 and pancreatic cancer cells (IC50 ~ 150 nM)2. Selinexor is being investigated as a possible chemotherapeutic in treating multiple types of cancer.3-8 Currently in clinical trials.
分子式:C17H11F6N7O
分子量:443.31
溶剂:DMSO (>25 mg/ml) Ethanol (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):CRM1/XPO1 nuclear export receptor inhibitor
Function / Pharmacology:Selinexor is a potent inhibitor of the nuclear export receptor, chromosome region maintenance 1 (CRM1; Exportin-1 (XPO1)). It exhibited potent growth suppression in various T-cell acute lymphoblastic leukemia (T-ALL) cells (IC50’s = 34-203 nM)1 and pancreatic cancer cells (IC50 ~ 150 nM)2. Selinexor is being investigated as a possible chemotherapeutic in treating multiple types of cancer.3-8 Currently in clinical trials.
