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Lomeguatrib
- 英文名称:Lomeguatrib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B11065
- cas:192441-08-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B11065 |
用途 | 科研检测 |
英文名称 | Lomeguatrib |
包装规格 | 1MG |
CAS编号 | 192441-08-0 |
别名 | Lomeguatrib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C10H8BrN5O3S
分子量:326.17
溶剂:DMSO (10 mg/ml)
性状:Off-white or beige solid
存储:-20°C
Activity (short version):MGMT inhibitor
Function / Pharmacology:Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7.
分子式:C10H8BrN5O3S
分子量:326.17
溶剂:DMSO (10 mg/ml)
性状:Off-white or beige solid
存储:-20°C
Activity (short version):MGMT inhibitor
Function / Pharmacology:Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7.