|
EED-226
- 英文名称：EED-226
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11069
- cas：2083627-02-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11069 |
| 用途 | 科研检测 |
| 英文名称 | EED-226 |
| 包装规格 | 1MG |
| CAS编号 | 2083627-02-3 |
| 别名 | EED-226 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C17H15N5O3S
分子量:369.40
溶剂:DMSO (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):PRC2 methyltransferase inhibitor
Function / Pharmacology:EED-226 is a potent (IC50 = 23.4 nM) and selective allosteric inhibitor of the EED subunit of the methyltransferase polycomb repressive complex 2 (PRC2).1,2 It caused drastic proliferation inhibition in lymphoma cells with EZH2 mutations and caused shrinkage and slower tumor growth in mice using a subcutaneous xenograft model of Karpas422.
分子式:C17H15N5O3S
分子量:369.40
溶剂:DMSO (25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):PRC2 methyltransferase inhibitor
Function / Pharmacology:EED-226 is a potent (IC50 = 23.4 nM) and selective allosteric inhibitor of the EED subunit of the methyltransferase polycomb repressive complex 2 (PRC2).1,2 It caused drastic proliferation inhibition in lymphoma cells with EZH2 mutations and caused shrinkage and slower tumor growth in mice using a subcutaneous xenograft model of Karpas422.
