纯度:98%,;NMR (Conforms)
分子式:C21H19FN4O
分子量:362.40
溶剂:DMSO (20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):HDAC3 inhibitor
Function / Pharmacology:RGFP966 is a selective inhibitor of HDAC3 (IC50 = 80 nM, no other HDACs inhibited at 15μM).1 It facilitates the extinction of cocaine-seeking behavior in mice and transforms subthreshold learning events into robust long-term memory, suggesting a potential therapeutic target for memory enhancement and neurodegenerative diseases.1-5