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BZ1
- 英文名称：BZ1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11082
- cas：2766623-38-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11082 |
| 用途 | 科研检测 |
| 英文名称 | BZ1 |
| 包装规格 | 1MG |
| CAS编号 | 2766623-38-3 |
| 别名 | BZ1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C13H15ClN4O
分子量:278.74
溶剂:DMSO (50 mg/ml); Ethanol (50 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):BPTF inhibitor
Function / Pharmacology:Potent (Kd = 6.3 nM; IC50 = 67 nM BPTF Alphascreen) inhibitor of the bromodomain PHD finger transcription factor (BPTF). It displays >350-fold selectivity over BET bromodomains. BZ1 sensitized 4T1 mouse breast cancer cells to doxorubicin treatment. BPTF inhibition represents a potential strategy for the inhibition of nucleosome remodeling factor (NURF) and exploration of its function.
分子式:C13H15ClN4O
分子量:278.74
溶剂:DMSO (50 mg/ml); Ethanol (50 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):BPTF inhibitor
Function / Pharmacology:Potent (Kd = 6.3 nM; IC50 = 67 nM BPTF Alphascreen) inhibitor of the bromodomain PHD finger transcription factor (BPTF). It displays >350-fold selectivity over BET bromodomains. BZ1 sensitized 4T1 mouse breast cancer cells to doxorubicin treatment. BPTF inhibition represents a potential strategy for the inhibition of nucleosome remodeling factor (NURF) and exploration of its function.
