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iJMJD6
- 英文名称：iJMJD6
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11084
- cas：899548-78-8
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11084 |
| 用途 | 科研检测 |
| 英文名称 | iJMJD6 |
| 包装规格 | 1MG |
| CAS编号 | 899548-78-8 |
| 别名 | iJMJD6 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% HPLC,;NMR (Conforms)
分子式:C16H11N3O2
分子量:277.28
溶剂:DMSO (>12 mg/ml with warming)
性状:Yellow solid
存储:-20°C
Activity (short version):Arginine demethylase JMJD6 inhibitor
Function / Pharmacology:Inhibitor of the arginine demethylase JMJD6 (IC50 = 220 nM) with selectivity over other JmjC domain-containing proteins.1 Exhibited antiproliferative effects in HeLa (EC50 = 1.49 μM), SMCC7721 (EC50 = 9.37 μM), and MCF7 (EC50 = 9.53 μM) cells.2 Displayed no cytotoxicity towards normal cervical, liver, and breast epithelial cells. iJMJD6 significantly suppressed tumor growth in a HeLa, SMCC7721, MCF7, MDA-MB-231, U87, and HCT116 mouse xenograft models.2
分子式:C16H11N3O2
分子量:277.28
溶剂:DMSO (>12 mg/ml with warming)
性状:Yellow solid
存储:-20°C
Activity (short version):Arginine demethylase JMJD6 inhibitor
Function / Pharmacology:Inhibitor of the arginine demethylase JMJD6 (IC50 = 220 nM) with selectivity over other JmjC domain-containing proteins.1 Exhibited antiproliferative effects in HeLa (EC50 = 1.49 μM), SMCC7721 (EC50 = 9.37 μM), and MCF7 (EC50 = 9.53 μM) cells.2 Displayed no cytotoxicity towards normal cervical, liver, and breast epithelial cells. iJMJD6 significantly suppressed tumor growth in a HeLa, SMCC7721, MCF7, MDA-MB-231, U87, and HCT116 mouse xenograft models.2
