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TETi76 ester
- 英文名称：TETi76 ester
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B11085
- cas：1451750-73-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B11085 |
| 用途 | 科研检测 |
| 英文名称 | TETi76 ester |
| 包装规格 | 1MG |
| CAS编号 | 1451750-73-4 |
| 别名 | TETi76 ester |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% TLC,;NMR (Conforms)
分子式:C10H16O5
分子量:216.23
溶剂:DMSO (100 mg/ml)
性状:Colorless oil
存储:-20°C
Activity (short version):TET inhibitor
Function / Pharmacology:Cell permeable inhibitor of TET dioxygenases (IC50s: TET1 = 1.5 μM; TET2 = 9.4 μM; TET3 = 8.8 μM), indirect (via cytosine hydroxymethylation) erasers of DNA methylation.1,2 TET2 is frequently mutated in myeloid neoplasms – TET2 inhibition with TETi76 restricted clonal outgrowth and induced apoptosis of TET2 mutants but not normal hematopoietic precursor cells in vitro and in vivo.
分子式:C10H16O5
分子量:216.23
溶剂:DMSO (100 mg/ml)
性状:Colorless oil
存储:-20°C
Activity (short version):TET inhibitor
Function / Pharmacology:Cell permeable inhibitor of TET dioxygenases (IC50s: TET1 = 1.5 μM; TET2 = 9.4 μM; TET3 = 8.8 μM), indirect (via cytosine hydroxymethylation) erasers of DNA methylation.1,2 TET2 is frequently mutated in myeloid neoplasms – TET2 inhibition with TETi76 restricted clonal outgrowth and induced apoptosis of TET2 mutants but not normal hematopoietic precursor cells in vitro and in vivo.
